A controller for qualifying image registration includes a memory that stores instructions; and a processor that executes the instructions. When executed by the processor, the instructions cause the controller to execute a process that includes receiving first imagery of a first modality and receiving second imagery of a second modality. The process executed by the controller also includes registering the first imagery of the first modality to the second imagery of the second modality to obtain an image registration. The image registration is subjected to an automated analysis as a qualifying process to qualify the image registration. The image registration is variably qualified when the image registration passes the qualifying process, and is not qualified when the image registration does not pass the qualifying process.