A display screen quality detection method, an apparatus, an electronic device and a storage medium. The method includes receiving a quality detection request sent by a console deployed on a display screen production line, where the quality detection request includes a display screen image captured by an image capturing device on the display screen production line, performing image preprocessing on the display screen image, and inputting the preprocessed display screen image into a defect detection model to obtain a defect detection result, where the defect detection model is obtained by training with a historical defect display screen image using a deep convolutional neural network structure and an instance segmentation algorithm, determining, according to the defect detection result, quality of a display screen corresponding to the display screen image. The technical solution has high defect detection accuracy, good system performance, and high business expansion capability.