- 专利标题： Imageable polymers, methods of making and methods of use thereof
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申请号： US16349458申请日： 2017-10-31
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公开(公告)号： US11382990B2公开(公告)日： 2022-07-12
- 发明人: Ayele H. Negussie , Bradford Johns Wood
- 申请人： The United States of America, as Represented by the Secretary, Department of Health and Human Services
- 申请人地址： US MD Bethesda
- 专利权人： The United States of America, as Represented by the Secretary, Department of Health and Human Services
- 当前专利权人： The United States of America, as Represented by the Secretary, Department of Health and Human Services
- 当前专利权人地址： US MD Bethesda
- 代理机构： McBee Moore & Vanik IP, LLC
- 国际申请： PCT/US2017/059406 WO 20171031
- 国际公布： WO2018/093566 WO 20180524
- 主分类号： A61K49/04
- IPC分类号： A61K49/04
摘要：
Described herein are X-ray imageable polymers such as polymeric particles comprising bismuth as a radiopacifying agent, methods of making the polymers, and methods of using the polymers. The imageable particles may comprise a covalently bound compound which chelates the bismuth, for example, through a combination of nitrogen and oxygen atoms.
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