Technologies for managing paravirtual network device queue and memory of a network computing device that includes multi-core processor, a multi-layer cache, a host, and a plurality of virtual machine instances. The host is assigned a processor core of the processor and may be configured to copy a received network packet to a last level cache of the multi-layer cache and determine one or more virtual machine instances configured to process the received network packet. Each virtual machine instance has been assigned a processor core of the processor and has been allocated a first level cache of the multi-level cache memory associated with the respective processor core. The host is additionally configured to inject an interrupt into each processor core of the determined virtual machine (s) which indicates to the virtual machine instance (s) that the received network packet is available to be processed.