- 专利标题： Identification of MHC class I phospho-peptide antigens from breast cancer utilizing SHLA technology and complementary enrichment strategies
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申请号： US16806374申请日： 2020-03-02
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公开(公告)号： US11414458B2公开(公告)日： 2022-08-16
- 发明人: Donald F. Hunt , Andrew Norris , Ann Michelle English , Jeffrey Shabanowitz , William H. Hilderbrand , Oriana E. Hawkins
- 申请人： Agenus Inc. , The Board of Regents of the University of Oklahoma
- 申请人地址： US MA Lexington; US OK Norman
- 专利权人： Agenus Inc.,The Board of Regents of the University of Oklahoma
- 当前专利权人： Agenus Inc.,The Board of Regents of the University of Oklahoma
- 当前专利权人地址： US MA Lexington; US OK Norman
- 代理机构： Dechert LLP
- 代理商 Andrew T Wilkins; Elizabeth A Browning
- 主分类号： C07K7/08
- IPC分类号： C07K7/08 ; C07K14/47 ; A61K39/00 ; C07K7/06 ; C07K16/18 ; A61K38/00
摘要：
The present invention describes novel tumor-specific phosphorylated peptides, nucleic acids encoding those peptides, and antibodies generated against said peptides. The genes, peptides, and antibodies described herein may be used as diagnostic indicators of the presence of breast cancer and/or used in therapeutics to treat breast cancer.
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