- 专利标题: Viral vectors for treating neurogenic detrusor overactivity
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申请号: US16312867申请日: 2017-06-23
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公开(公告)号: US11414666B2公开(公告)日: 2022-08-16
- 发明人: François Giuliano , Alberto Epstein , Olivier Le Coz , Alejandro Aranda
- 申请人: UNIVERSITE DE VERSAILLES-ST QUENTIN EN YVELINES , ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS
- 申请人地址: FR Versailles; FR Paris
- 专利权人: UNIVERSITE DE VERSAILLES-ST QUENTIN EN YVELINES,ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS
- 当前专利权人: UNIVERSITE DE VERSAILLES-ST QUENTIN EN YVELINES,ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS
- 当前专利权人地址: FR Versailles; FR Paris
- 代理机构: Birch, Stewart, Kolasch & Birch, LLP
- 优先权: EP16305765.6 20160623
- 国际申请: PCT/EP2017/065587 WO 20170623
- 国际公布: WO2017/220800 WO 20171228
- 主分类号: A61K38/16
- IPC分类号: A61K38/16 ; A61P13/00 ; A61K38/48 ; C12N15/869 ; C12N15/113 ; A61P13/06 ; A61K38/17 ; A61K38/45 ; A61K38/51 ; C12N15/86
摘要:
The present invention provides a method and a pharmaceutical composition for the treatment of the NDO comprising the viral expression vector carrying a transcription cassette that harbors transgene(s) inhibiting/silencing neurotransmission or synaptic transmission of afferent neurons.
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