Invention Grant
- Patent Title: Rebamipide prodrugs, preparation method and use thereof
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Application No.: US14411390Application Date: 2013-06-26
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Publication No.: US11420963B2Publication Date: 2022-08-23
- Inventor: Eui Hwan Cho , Sung Ju Choi , Sung Woo Lee , Hee Jong Shin , Ho Seok Kwon , Jae Woong Lee , Jeong Ho Joo , Hyun Tae Kim , Woo Heon Song , Jong Bae Yoon , Ki Seok Park , Ho Joon Park , Ho Tae Nam
- Applicant: SAMJIN PHARMACEUTICAL CO., LTD. , ASTECH. CO., LTD.
- Applicant Address: KR Seoul; KR Gyeonggi-do
- Assignee: SAMJIN PHARMACEUTICAL CO., LTD.,ASTECH. CO., LTD.
- Current Assignee: SAMJIN PHARMACEUTICAL CO., LTD.,ASTECH. CO., LTD.
- Current Assignee Address: KR Seoul; KR Gyeonggi-do
- Agency: Cantor Colburn LLP
- Priority: KR10-2012-0068394 20120626
- International Application: PCT/KR2013/005622 WO 20130626
- International Announcement: WO2014/003424 WO 20140103
- Main IPC: C07D417/12
- IPC: C07D417/12 ; C07D215/227 ; C07D413/12 ; A61K31/4704 ; C07D401/12 ; C07D405/12 ; C07D409/12
Abstract:
Disclosed are a novel rebamipide prodrug, a method for preparing the same, and use thereof. Also, a pharmaceutical composition comprising the novel rebamipide prodrug as an active ingredient is provided. The rebamipide prodrug is increased 25-fold in absorption rate compared to rebamipide itself, and can be applied to the prophylaxis or therapy of gastric ulcer, acute gastritis, chronic gastritis, xerophthalmia, cancer, osteoarthritis, rheumatoid arthritis, or obesity.
Public/Granted literature
- US20150141409A1 NOVEL REVAMIPIDE PRODRUGS, PREPARATION METHOD AND USE THEREOF Public/Granted day:2015-05-21
Information query
