- 专利标题： Piperidinyl-methyl-purineamines as NSD2 inhibitors and anti-cancer agents
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申请号： US17327226申请日： 2021-05-21
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公开(公告)号： US11420970B1公开(公告)日： 2022-08-23
- 发明人: Haibing Deng , Jinbiao Liu , Counde Oyang , Ce Wang , Qitao Xiao , Guoliang Xun , Haiqiang Zeng
- 申请人： NOVARTIS AG
- 申请人地址： CH Basel
- 专利权人： NOVARTIS AG
- 当前专利权人： NOVARTIS AG
- 当前专利权人地址： CH Basel
- 代理机构： Dechert LLP
- 优先权： WOPCT/CN2019/100542 20190814
- 主分类号： C07D473/34
- IPC分类号： C07D473/34
摘要：
The present invention provides a compound of Formula (I): or an enantiomer, an enantiomeric mixture, or a pharmaceutically acceptable salt thereof; wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds; and methods of using such compounds for treating a disease or condition mediated by nuclear SET domain-containing protein 2 (NSD2).
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