Invention Grant
- Patent Title: Acid-alpha glucosidase variants and uses thereof
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Application No.: US16332373Application Date: 2017-09-12
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Publication No.: US11421211B2Publication Date: 2022-08-23
- Inventor: Federico Mingozzi , Giuseppe Ronzitti , Dwight D. Koeberl , Sang-Oh Han
- Applicant: GENETHON , SORBONNE UNIVERSITE , DUKE UNIVERSITY
- Applicant Address: FR Evry; FR Paris; US NC Durham
- Assignee: GENETHON,SORBONNE UNIVERSITE,DUKE UNIVERSITY
- Current Assignee: GENETHON,SORBONNE UNIVERSITE,DUKE UNIVERSITY
- Current Assignee Address: FR Evry; FR Paris; US NC Durham
- Agency: Saliwanchik, Lloyd & Eisenschenk
- Priority: EP16306148 20160912
- International Application: PCT/EP2017/072942 WO 20170912
- International Announcement: WO2018/046772 WO 20180315
- Main IPC: C12N15/86
- IPC: C12N15/86 ; C12N9/24 ; C12N9/26 ; A61K38/47
Abstract:
The present invention relates to variants of acid-alpha glucosidase and uses thereof. Said variants are sequence-optimized and/or are linked to a heterogenous signal peptide.
Public/Granted literature
- US20190390184A1 ACID-ALPHA GLUCOSIDASE VARIANTS AND USES THEREOF Public/Granted day:2019-12-26
Information query
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