A method of operating a communication device including a processor and a memory, the method comprises feeding back a downlink communication signal subjected to analog signal processing, generating signal modification information according to a comparison result of the fed-back downlink communication signal and a downlink communication signal before the analog signal processing, generating an interference cancellation signal for canceling interference occurring in an uplink communication signal by the downlink communication signal based on the generated signal modification information and canceling interference occurring in the uplink communication signal by using the generated interference cancellation signal.