Provided are an image processing apparatus, a program and an image processing method capable of avoiding interference with the function of another program. An image processing apparatus includes a position information detection unit configured to detect position information indicating a position on a display, a region position setting unit configured to set the position of the region of interest on the display based on the position information, and an image processing unit configured to perform image process on at least one image among an image inside of the region of interest and an image outside of the region of interest. The region position setting unit, when the position information is changed with the image process, sets the position of the region of interest based on the position information immediately before the change.