Systems and methods related to controlling clock signals for clocking shader engines modules (SEs) and non-shader-engine modules (nSEs) of a graphics processing unit (GPU) are provided. One or more dividers receive a clock signal CLK and output a clock signal CLKA to the SEs and output a clock signal CLKB to the nSEs. The frequencies of CLKA and CLKB are independently selected based on sets of performance counter data monitored at the SEs and nSEs, respectively. The clock signal frequency for either the SEs or the nSEs is reduced when the corresponding sets of performance counter data indicates a comparatively lower processing workload for the SEs or for the nSEs.