Methods, systems, and computer-readable media for automated problem detection for machine learning models are disclosed. A machine learning analysis system receives data associated with use of a machine learning model. The data was collected by a machine learning inference system and comprises input to the model or a plurality of inferences representing output of the machine learning model. The machine learning analysis system performs analysis of the data associated with the use of the machine learning model. The machine learning analysis system detects one or more problems associated with the use of the machine learning model based at least in part on the analysis. The machine learning analysis system initiates one or more remedial actions associated with the one or more problems associated with the use of the machine learning model.