Invention Grant
- Patent Title: Image analysis of epithelial component of histologically normal prostate biopsies predicts the presence of cancer
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Application No.: US16723595Application Date: 2019-12-20
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Publication No.: US11449987B2Publication Date: 2022-09-20
- Inventor: David Frazier Jarrard , Bing Yang , Peter LaViolette
- Applicant: Wisconsin Alumni Research Foundation , The Medical College of Wisconsin, Inc.
- Applicant Address: US WI Madison; US WI Milwaukee
- Assignee: Wisconsin Alumni Research Foundation,The Medical College of Wisconsin, Inc.
- Current Assignee: Wisconsin Alumni Research Foundation,The Medical College of Wisconsin, Inc.
- Current Assignee Address: US WI Madison; US WI Milwaukee
- Agency: DeWitt LLP
- Agent Daniel A. Blasiole
- Main IPC: G06T7/00
- IPC: G06T7/00 ; G16H30/40 ; G16H50/30 ; G01N1/30

Abstract:
A method of detecting the presence of a prostate cancer in a human subject comprising the steps of (a) obtaining a histologically normal prostate tissue sample from the patient and (b) quantifying the epithelial thickness or gland lumen roundness of the tissue, wherein an increase in epithelial thickness or a decrease in gland lumen roundness indicates the presence of prostate cancer or a prostate cancer field defect.
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