A method and system for providing end-to-end multi-task denoising for joint signal distortion ratio (SDR) and perceptual evaluation of speech quality (PESQ) optimization is herein disclosed. According to one embodiment, an method includes receiving a noisy signal, generating a denoised output signal, determining a signal distortion ratio (SDR) loss function based on the denoised output signal, determining a perceptual evaluation of speech quality (PESQ) loss function based on the denoised output signal, and optimizing an overall loss function based on the PESQ loss function and the SDR loss function.