A lead fixation device for securing a portion of a lead relative to a surface of a skull includes a skull attachment member having an upper surface and a lower surface, a locking member having an upper surface and a lower surface and associated with the skull attachment member, and a passageway associated with the locking member and configured to receive the portion of the lead. The skull attachment member and the locking member are configured to rotate relative to each other to transition the lead fixation device between a closed state wherein the lower surface of the skull attachment member and the lower surface of the locking member are generally aligned in a common plane, and an opened state wherein the lower surface of the skull attachment member and the lower surface of the locking member are not aligned in a common plane.