A method and apparatus for transmitting adaptive video in real time using a content-aware neural network are disclosed. At least one embodiment provides a method performed by a server for transmitting an adaptive video in real time by using content-aware deep neural networks (DNNs), including downloading a video, encoding a downloaded video for each of at least one resolution, dividing an encoded video into video chunks of a predetermined size, training the content-aware DNNs by using encoded video, generating a configuration or manifest file containing information on trained content-aware DNNs and information on the encoded video, and transmitting the configuration file upon a request of a client.