- 专利标题： Compound having ERK kinase inhibitory activity and use thereof
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申请号： US16652148申请日： 2018-09-29
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公开(公告)号： US11465984B2公开(公告)日： 2022-10-11
- 发明人: Lei Li , Meiyu Geng , Ying Huang , Jian Ding , Qiong Zhang , Min Huang , Shuai Tang , Ning Shen , Yi Chen
- 申请人： SHANGHAI HAIHE PHARMACEUTICAL CO., LTD. , SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES
- 申请人地址： CN Shanghai; CN Shanghai
- 专利权人： SHANGHAI HAIHE PHARMACEUTICAL CO., LTD.,SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES
- 当前专利权人： SHANGHAI HAIHE PHARMACEUTICAL CO., LTD.,SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES
- 当前专利权人地址： CN Shanghai; CN Shanghai
- 代理机构： Hoxie & Associates LLC
- 优先权： CN201710915493.5 20170930
- 国际申请： PCT/CN2018/108762 WO 20180929
- 国际公布： WO2019/062949 WO 20190404
- 主分类号： C07D401/14
- IPC分类号： C07D401/14 ; C07D403/14 ; C07D405/14
摘要：
The invention relates to a compound of formula (I): wherein variables are as defined in the specification. The compound is an inhibitor of an ERK kinase, e.g. ERK1 and/or ERK2 kinase. The invention also relates to the use of the compound and a method for preparing the compound, and a pharmaceutical composition containing the compound.
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