- 专利标题: ERK inhibitor and use thereof
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申请号: US16973335申请日: 2019-06-06
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公开(公告)号: US11466013B2公开(公告)日: 2022-10-11
- 发明人: Hao Wu , Wei Gu , Xiaojing Tang , Wei Wang , Bo Zhan , Dongjie Feng , Yongxin Ke , Zhongyan Chen , Yifei Shen , Wenmao Wu , Xintao Zhao , Hong Lan , Jiabing Wang , Lieming Ding
- 申请人: Betta Pharmaceuticals Co., LTD
- 申请人地址: CN Zhejiang
- 专利权人: Betta Pharmaceuticals Co., LTD
- 当前专利权人: Betta Pharmaceuticals Co., LTD
- 当前专利权人地址: CN Zhejiang
- 代理机构: Umberg Zipser LLP
- 代理商 Jason Tejani
- 优先权: WOPCT/CN2018/090385 20180608,WOPCT/CN2018/120975 20181213
- 国际申请: PCT/CN2019/090221 WO 20190606
- 国际公布: WO2019/233457 WO 20191212
- 主分类号: C07D487/04
- IPC分类号: C07D487/04 ; A61P35/00 ; C07D401/04 ; C07D403/14 ; C07D417/04 ; C07D487/20 ; C07D491/20 ; C07D513/04 ; C07D519/00
摘要:
Disclosed are a compound (as shown in formula I) as an extracellular signal-regulated kinase (ERK) inhibitor, a pharmaceutical composition thereof, a preparation method therefor, and use thereof in treating ERK-mediated diseases. Said compound plays a role by regulating a plurality of processes such as cell proliferation, apoptosis, migration and angiogenesis.
公开/授权文献
- US20210261552A1 ERK INHIBITOR AND USE THEREOF 公开/授权日:2021-08-26
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