- 专利标题: Dual-probe digital droplet PCR strategy for specific detection of tissue-specific circulating DNA molecules
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申请号: US16630593申请日: 2018-07-13
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公开(公告)号: US11466323B2公开(公告)日: 2022-10-11
- 发明人: Yuval Dor , Ruth Shemer , Benjamin Glaser , Judith Magenheim
- 申请人: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. , HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD.
- 申请人地址: IL Jerusalem; IL Jerusalem
- 专利权人: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.,HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD.
- 当前专利权人: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.,HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD.
- 当前专利权人地址: IL Jerusalem; IL Jerusalem
- 代理机构: The Roy Gross Law Firm, LLC
- 代理商 Roy Gross
- 国际申请: PCT/IL2018/050772 WO 20180713
- 国际公布: WO2019/012544 WO 20190117
- 主分类号: C12Q1/6876
- IPC分类号: C12Q1/6876 ; C12Q1/6827 ; C12Q1/686 ; C12Q1/6869
摘要:
A digital droplet PCR method of analyzing the methylation status of methylation sites of a double-stranded DNA molecule which comprises at least two methylation sites per single strand of the double-stranded DNA molecule is disclosed.
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