An error correction method and a time-interleaved analog-to-digital converter (TIADC) are provided. The method is applied to a TIADC that includes a plurality of analog-to-digital converters (ADCs), and the method includes: determining whether a current value of a codeword of a first ADC in the plurality of ADCs is within a preset range; when the current value of the codeword of the first ADC is not within the preset range, adjusting a plurality of codewords that are in a one-to-one correspondence with the plurality of ADCs; and controlling a clock frequency division circuit to generate, by using a plurality of adjusted codewords, a plurality of sampling clocks that are in a one-to-one correspondence with the plurality of ADCs. In embodiments of this application, a sampling time-period skew existing between ADCs may be adjusted by adjusting codewords corresponding to the ADCs.