A touch display panel including a pixel defining layer, a first light emitting structure, a second light emitting structure, a first light sensing device and a touch electrode layer is provided. The pixel defining layer has a first pixel opening and a second pixel opening. The first light sensing device is adjacently disposed on a first side of the first pixel opening. A first edge defining a first electrode opening of the touch electrode layer and a second edge defining the first pixel opening of the pixel defining layer have a first spacing on the first side of the first pixel opening. A third edge defining a second electrode opening of the touch electrode layer and a fourth edge defining the second pixel opening of the pixel defining layer have a second spacing on a side of the second pixel opening. The first spacing is greater than the second spacing.