Invention Grant
![1H-pyrazolo[4,3-b]pyridines as PDE1 inhibitors](/docs/US/2022-11-08/US11491140B2/abs.jpg.600x600.jpg)
- Patent Title: 1H-pyrazolo[4,3-b]pyridines as PDE1 inhibitors
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Application No.: US16943496Application Date: 2020-07-30
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Publication No.: US11491140B2Publication Date: 2022-11-08
- Inventor: Jan Kehler , Karsten Juhl , Mauro Marigo , Paulo Jorge Vieira Vital , Mikkel Jessing , Morten Langgård , Lars Kyhn Rasmussen , Carl Martin Sebastian Clementson
- Applicant: H. Lundbeck A/S
- Applicant Address: DK Valby
- Assignee: H. Lundbeck A/S
- Current Assignee: H. Lundbeck A/S
- Current Assignee Address: DK Valby
- Agency: Wolf, Greenfield & Sacks, P.C.
- Priority: DKPA201600397 20160704,DKPA201600612 20161011,DKPA201700236 20170404
- Main IPC: C07D401/14
- IPC: C07D401/14 ; A61K31/437 ; A61K31/4162 ; C07D471/04 ; A61K31/4745 ; C07D413/04 ; C07D305/06 ; C07D401/04
![1H-pyrazolo[4,3-b]pyridines as PDE1 inhibitors](/abs-image/US/2022/11/08/US11491140B2/abs.jpg.150x150.jpg)
Abstract:
The present invention provides 1H-pyrazolo[4,3-b]pyridin-7-amines of formula (1) as PDE1 inhibitors and their use as a medicament, in particular for the treatment of neurodegenerative disorders and psychiatric disorders.
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