![Salt of a pyrimido[6,1-A]isoquinolin-4-one compound](/docs/US/2022-11-08/US11491155B2/abs.jpg.600x600.jpg)
- 专利标题： Salt of a pyrimido[6,1-A]isoquinolin-4-one compound
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申请号： US16580515申请日： 2019-09-24
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公开(公告)号： US11491155B2公开(公告)日： 2022-11-08
- 发明人: Peter Lionel Spargo , Edward James French , Julian Scott Northen , John Mykytiuk
- 申请人： VERONA PHARMA PLC
- 申请人地址： GB Cardiff
- 专利权人： VERONA PHARMA PLC
- 当前专利权人： VERONA PHARMA PLC
- 当前专利权人地址： GB Cardiff
- 代理机构： MH2 Technology Law Group, LLP
- 优先权： GB1502260 20150211
- 主分类号： A61K31/513
- IPC分类号： A61K31/513 ; C07D471/04 ; A61K9/00 ; A61K31/185 ; A61K31/519 ; A61K45/06
![Salt of a pyrimido[6,1-A]isoquinolin-4-one compound](/abs-image/US/2022/11/08/US11491155B2/abs.jpg.150x150.jpg)
摘要：
The present invention relates to a pharmaceutically acceptable acid addition salt of: (i) 9,10-dimethoxy-2-(2,4,6-tri-methylphenylimino)-3-(N-carbamoyl-2-aminoethyl)-3,4,6,7-tetrahydro-2H-pyrimido[6,1-a]isoquinolin-4-one (RPL554); and (ii) ethane-1,2-disulfonic acid, ethanesulfonic acid, methanesulfonic acid, benzenesulfonic acid, p-toluenesulfonic acid, hydrochloric acid, hydrobromic acid, phosphoric acid or sulfuric acid.
公开/授权文献
- US20200016158A1 SALT OF A PYRIMIDO[6,1-A]ISOQUINOLIN-4-ONE COMPOUND 公开/授权日：2020-01-16
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