Invention Grant
- Patent Title: Treating patients harboring an isocitrate dehydrogenase 1 (IDH-1) mutation
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Application No.: US17112269Application Date: 2020-12-04
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Publication No.: US11497743B2Publication Date: 2022-11-15
- Inventor: Patrick F. Kelly , Alan Collis , Jeff Davis , Duncan Walker , Susan Ashwell , Blythe Thomson , Wei Lu
- Applicant: FORMA Therapeutics, Inc.
- Applicant Address: US MA Watertown
- Assignee: FORMA Therapeutics, Inc.
- Current Assignee: FORMA Therapeutics, Inc.
- Current Assignee Address: US MA Watertown
- Agent James J. Diehl
- Main IPC: A61K31/4709
- IPC: A61K31/4709 ; A61P35/02 ; C12Q1/686 ; C12Q1/6886
Abstract:
Methods of treating patients diagnosed with AML or MDS harboring mutant IDH-1 include detecting an IDH1 mutation and the therapeutic administration of an inhibitor of a mutant IDH-1 as a single agent, or in combination with azacitidine (AZA) or cytarabine.
Public/Granted literature
- US20210085669A1 TREATING PATIENTS HARBORING AN ISOCITRATE DEHYDROGENASE 1 (IDH-1) MUTATION Public/Granted day:2021-03-25
Information query
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