- 专利标题： Dopamine D2 receptor ligands
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申请号： US16826028申请日： 2020-03-20
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公开(公告)号： US11498896B2公开(公告)日： 2022-11-15
- 发明人: Edward Holson , Florence Fevrier Wagner , Michel Weiwer , Edward Scolnick , Michelle Palmer , Luka Dordevic , Michael C. Lewis , Jennifer Q. Pan , Yan-Ling Zhang , Qihong Xu
- 申请人： The Broad Institute, Inc. , Massachusetts Institute of Technology
- 申请人地址： US MA Cambridge; US MA Cambridge
- 专利权人： The Broad Institute, Inc.,Massachusetts Institute of Technology
- 当前专利权人： The Broad Institute, Inc.,Massachusetts Institute of Technology
- 当前专利权人地址： US MA Cambridge; US MA Cambridge
- 代理机构： Wolf, Greenfield & Sacks, P.C.
- 主分类号： C07D405/06
- IPC分类号： C07D405/06 ; A61K31/453 ; C07D207/12 ; C07D401/04 ; C07D401/06 ; C07D401/12 ; C07D413/12 ; C07D417/12 ; C07D451/06 ; C07D471/10 ; C07D491/048 ; C07D491/052 ; C07D491/056 ; C07D491/107 ; C07D211/18 ; C07D211/38 ; C07D211/42 ; C07D211/48 ; C07D211/58 ; C07D211/62 ; C07D211/70 ; C07D211/22 ; A61P25/18 ; A61P25/16 ; C07K14/705
摘要：
The present invention relates to novel dopamine D2 receptor ligands. The invention further relates to functionally-biased dopamine D2 receptor ligands and the use of these compounds for treating or preventing central nervous system and systemic disorders associated with dysregulation of dopaminergic activity.
公开/授权文献
- US20210147355A1 DOPAMINE D2 RECEPTOR LIGANDS 公开/授权日：2021-05-20
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