Invention Grant
- Patent Title: Neuroactive steroids, compositions, and uses thereof
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Application No.: US16843822Application Date: 2020-04-08
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Publication No.: US11498940B2Publication Date: 2022-11-15
- Inventor: Gabriel Martinez Botella , Boyd L. Harrison , Albert Jean Robichaud , Francesco G. Salituro , Robert Jason Herr , Robert Borbo Kargbo
- Applicant: Sage Therapeutics, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Sage Therapeutics, Inc.
- Current Assignee: Sage Therapeutics, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Honigman LLP
- Agent Andrew N. Weber; Jonathan P. O'Brien
- Main IPC: C07J43/00
- IPC: C07J43/00 ; A61K31/58 ; C07J7/00 ; A61K45/06 ; C07J21/00 ; C07J1/00 ; C07J13/00
Abstract:
Described herein are neuroactive steroids of the Formula (I): or a pharmaceutically acceptable salt thereof; wherein -------, R1, R2, R5, A and L are as defined herein. Such compounds are envisioned, in certain embodiments, to behave as GABA modulators. The present invention also provides pharmaceutical compositions comprising a compound of the present invention and methods of use and treatment, e.g., such for inducing sedation and/or anesthesia.
Public/Granted literature
- US20210061848A1 NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF Public/Granted day:2021-03-04
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