Methods and systems are provided for determining scan settings for a localizer scan based on a magnetic resonance (MR) calibration image. In one example, a method for magnetic resonance imaging (MRI) includes acquiring an MR calibration image of an imaging subject, mapping, by a trained deep neural network, the MR calibration image to a corresponding anatomical region of interest (ROI) attribute map for an anatomical ROI of the imaging subject, adjusting one or more localizer scan parameters based on the anatomical ROI attribute map, and acquiring one or more localizer images of the anatomical ROI according to the one or more localizer scan parameters.