Invention Grant
- Patent Title: Metal-nucleic acid nanoparticle, preparation method therefor and use thereof
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Application No.: US16764551Application Date: 2019-04-03
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Publication No.: US11510879B2Publication Date: 2022-11-29
- Inventor: Lele Li , Congli Wang , Zhenghan Di
- Applicant: NATIONAL CENTER FOR NANOSCIENCE AND TECHNOLOGY, CHINA
- Applicant Address: CN Beijing
- Assignee: NATIONAL CENTER FOR NANOSCIENCE AND TECHNOLOGY, CHINA
- Current Assignee: NATIONAL CENTER FOR NANOSCIENCE AND TECHNOLOGY, CHINA
- Current Assignee Address: CN Beijing
- Agency: McDonald Hopkins LLC
- Priority: CN201811277020.8 20181030
- International Application: PCT/CN2019/081244 WO 20190403
- International Announcement: WO2020/087867 WO 20200507
- Main IPC: A61K9/51
- IPC: A61K9/51 ; B82Y5/00 ; B82Y40/00
Abstract:
The present application relates to a metal-nucleic acid nanoparticle which is a nanoparticle having a spherical structure formed by assembly of metal ions with nucleic acids via coordination. The preparation thereof is mixing a metal ion solution with a nucleic acid solution to obtain a mixture followed by vortex, heating, centrifugation, washing with water and resuspension to obtain the metal-nucleic acid nanoparticles.
Public/Granted literature
- US20210378975A1 METAL-NUCLEIC ACID NANOPARTICLE, PREPARATION METHOD THEREFOR AND USE THEREOF Public/Granted day:2021-12-09
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