Disclosed in the present application are a method for reducing SGLTE coupling de-sense and a mobile terminal, the method including: filtering out an LTE network frequency band in a signal transmitted by a signal transmission end of a GSM; and filtering out a network frequency band in a signal of a signal reception end accessing the GSM other than a GSM network frequency band. Employing the present application may eliminate mutual interference between a GSM signal and an LTE signal due to the GSM network frequency band and the LTE network frequency band getting too close to each other, which greatly alleviates SGLTE mobile terminal coupling de-sense situation.