An object holder with quick-release anchoring capability includes an object carrier having an object carrier base. A vacuum release actuator on the object carrier base is displaceable to separate from the object. An anchor member carried by vacuum release actuator includes outer and inner seal members and an interconnecting vent port. The outer seal member is arranged to form a substantially airtight seal with the reference surface that defines an outer controlled pressure zone. The inner seal member is arranged to form a substantially airtight seal with the object that defines an inner controlled pressure zone. The vent port extends between the outer and inner controlled pressure zones. During operation, the controlled pressure zones can be vented by manipulating the object carrier away from the reference surface to separate the object and the vacuum release actuator until the inner seal member breaks its substantially airtight seal with the object.