The disclosure relates to a communication technique and a system for combining a 5G communication system with IoT technology to support a higher data rate after a 4G system. Based on 5G communication and IoT-related technologies, the disclosure may be applied to intelligent services such as smart homes, smart buildings, smart cities, smart or connected cars, healthcare, digital education, retail, and security and safety related services. The disclosure provides a method and apparatus that enable a communication device supporting full duplex to cancel the self-interference signal in the digital domain.