Invention Grant
- Patent Title: Isoindolines as HDAC inhibitors
-
Application No.: US17049094Application Date: 2019-04-18
-
Publication No.: US11535607B2Publication Date: 2022-12-27
- Inventor: Xiaozhang Zheng , Matthew W. Martin , Pui Yee Ng , Jennifer R. Thomason , Bingsong Han , Aleksandra Rudnitskaya , David R. Lancia, Jr.
- Applicant: Valo Health, Inc.
- Applicant Address: US MA Boston
- Assignee: Valo Health, Inc.
- Current Assignee: Valo Health, Inc.
- Current Assignee Address: US MA Boston
- Agency: Choate, Hall & Stewart LLP
- Agent John P. Rearick
- International Application: PCT/US2019/028026 WO 20190418
- International Announcement: WO2019/204550 WO 20191024
- Main IPC: C07D403/04
- IPC: C07D403/04 ; C07D209/10 ; C07D209/44 ; C07D401/04 ; C07D401/12 ; C07D413/04 ; C07D413/12 ; C07D417/04 ; C07D471/04 ; C07D498/04 ; C07D513/04

Abstract:
The present disclosure relates to inhibitors of zinc-dependent histone deacetylases (HDACs), having the formula: (I) wherein Z, X1, X2, Y1, Y2, Y3, L, Z, and R are described herein.
Public/Granted literature
- US20210253555A1 ISOINDOLINES AS HDAC INHIBITORS Public/Granted day:2021-08-19
Information query