Aspects of the technology described herein related to an ultrasound processing unit (UPU) including gray-coding circuitry configured to convert standard binary-coded digital ultrasound signals to gray-coded digital ultrasound signals and gray-decoding circuitry coupled to the gray-coding circuitry and configured to convert the gray-coded digital ultrasound signals to standard binary-coded digital ultrasound signals. The UPU may include an analog portion, a digital portion, and a data bus configured to route the gray-coded digital ultrasound signals from the analog portion to the digital portion subsequent to converting the standard binary-coded digital ultrasound signals to the gray-coded digital ultrasound signals. The analog portion may include multiple analog front-ends (AFEs), the gray-coding circuitry, and an analog-to-digital converter. The digital portion may include the gray-decoding circuitry. A data bus from one AFE may pass over another AFE.