The present application relates to the technical field of loudspeakers. Disclosed are a loudspeaker device, a method, apparatus and device for adjusting the sound effect thereof, and a medium. The method is used for increasing the diversity of the sound effect of the loudspeaker device, and comprises: determining the spatial distribution state of multiple loudspeaker units in the loudspeaker device; determining a sound effect mode corresponding to the spatial distribution state; and adjusting the sound effect of the loudspeaker device according to the sound effect mode. According to the present application, the sound effect mode is accordingly adjusted according to the spatial distribution state of multiple loudspeaker units in the loudspeaker device. In this way, when the spatial distribution state changes, the sound effect mode of the loudspeaker device also changes, thereby overcoming the defect of the single sound effect of the loudspeaker device, i.e., according to the present application, the diversity of the sound effect of the loudspeaker device can be increased efficiently.