- Patent Title: Fc binding proteins with cysteine in the c-terminal helical region
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Application No.: US16965833Application Date: 2019-01-28
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Publication No.: US11548929B2Publication Date: 2023-01-10
- Inventor: Erik Fiedler , Ulrich Haupts
- Applicant: Repligen Corporation
- Applicant Address: US MA Waltham
- Assignee: Repligen Corporation
- Current Assignee: Repligen Corporation
- Current Assignee Address: US MA Waltham
- Agency: KDB Firm PLLC
- Priority: EP18154731 20180201
- International Application: PCT/US2019/015433 WO 20190128
- International Announcement: WO2019/152318 WO 20190808
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C07K14/735 ; C07K1/14
Abstract:
The present invention relates to Fc binding proteins comprising one or more domains with Cysteine in the C-terminal helical region. The invention further relates to affinity matrices comprising the Fc binding proteins of the invention. The invention also relates to a use of these Fc binding proteins or affinity matrices for affinity purification of immunoglobulins and to methods of affinity purification using the Fc binding proteins of the invention.
Public/Granted literature
- US20210054044A1 FC BINDING PROTEINS WITH CYSTEINE IN THE C-TERMINAL HELICAL REGION Public/Granted day:2021-02-25
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