Methods, computer readable media, and devices for dynamic personalized API assembly are provided. One method may include receiving a data query from a client by a CDN, parsing the data query to generate a modified data query, transmitting the modified data query to an origin server, receiving a query response from the origin server, generating a modified query response based on the query response, and sending the modified query response to the client. Another method may include receiving an API call by an origin server, generating an API response by creating a payload file and adding markup directives indicating whether content is cacheable, and transmitting the API response.