Invention Grant
- Patent Title: Substituted pyrrolo[2,3-d]pyrimidines compounds as ret kinase inhibitors
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Application No.: US16962345Application Date: 2019-01-18
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Publication No.: US11603374B2Publication Date: 2023-03-14
- Inventor: James F. Blake , Donghua Dai , Julia Haas , Yutong Jiang , Gabrielle R. Kolakowski , Elizabeth A. McFaddin , Megan L. McKenney , Andrew T. Metcalf , David A. Moreno , Brett Prigaro , Ginelle A. Ramann , Li Ren
- Applicant: Array BioPharma Inc.
- Applicant Address: US CO Boulder
- Assignee: Array BioPharma Inc.
- Current Assignee: Array BioPharma Inc.
- Current Assignee Address: US CO Boulder
- Agency: Meunier Carlin & Curfman LLC
- International Application: PCT/US2019/014248 WO 20190118
- International Announcement: WO2019/143977 WO 20190725
- Main IPC: C07D487/04
- IPC: C07D487/04
![Substituted pyrrolo[2,3-d]pyrimidines compounds as ret kinase inhibitors](/abs-image/US/2023/03/14/US11603374B2/abs.jpg.150x150.jpg)
Abstract:
Provided herein are compounds of the Formula I: [INSERT FORMULA I] and tautomers, stereoisomers and pharmaceutically acceptable salts and solvates thereof, wherein R1, R2 and Ry have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders.
Public/Granted literature
- US20200339589A1 SUBSTITUTED PYRROLO[2,3-D]PYRIMIDINES COMPOUNDS AS RET KINASE INHIBITORS Public/Granted day:2020-10-29
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