- 专利标题： Method of predicting differentiation potential of iPS cells into cartilage cells based on gene expression profiles
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申请号： US16620647申请日： 2018-06-08
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公开(公告)号： US11603563B2公开(公告)日： 2023-03-14
- 发明人: Makoto Watanabe , Taka-Aki Sato , Junya Toguchida
- 申请人： Shimadzu Corporation , Kyoto University
- 申请人地址： JP Kyoto; JP Kyoto
- 专利权人： Shimadzu Corporation,Kyoto University
- 当前专利权人： Shimadzu Corporation,Kyoto University
- 当前专利权人地址： JP Kyoto; JP Kyoto
- 代理机构： Morgan, Lewis & Bockius LLP
- 优先权： JPJP2017-114804 20170610
- 国际申请： PCT/JP2018/022116 WO 20180608
- 国际公布： WO2018/225868 WO 20181213
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C12Q1/6876
摘要：
Provided is a method of predicting differentiation potential of undifferentiated iPS cells into cartilage cells. Provided is a genetic marker for predicting differentiation potential of undifferentiated iPS cells into cartilage cells. A method of predicting differentiation potential of undifferentiated iPS cells into cartilage cells based on gene expression data of the undifferentiated iPS cells. A method of predicting differentiation potential of undifferentiated iPS cells into cartilage cells by predicting differentiation potential of the iPS cells into neural crest cells (NC cells) based on gene expression data of the undifferentiated iPS cells.
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