- Patent Title: Systems and methods for single-molecule detection using nanopores
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Application No.: US14837514Application Date: 2015-08-27
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Publication No.: US11624727B2Publication Date: 2023-04-11
- Inventor: Jacob Rosenstein , Kenneth L. Shepard
- Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
- Applicant Address: US NY New York
- Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
- Current Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
- Current Assignee Address: US NY New York
- Agency: Hunton Andrews Kurth LLP
- Main IPC: G01N27/447
- IPC: G01N27/447 ; B82Y5/00 ; C12Q1/6869 ; B82Y15/00 ; G01N33/68 ; G01N33/487
Abstract:
A system and method for detecting a single-molecule using an integrated circuit which includes at least one membrane having a nanopore located between first and second reservoirs and a low-noise preamplifier having an electrode formed on the surface thereof is provided. The method includes passing a target molecule through the nanopore, and measuring a current through the nanopore to detect the presence of a biomolecular entity, if any.
Public/Granted literature
- US20150369776A1 SYSTEMS AND METHODS FOR SINGLE-MOLECULE DETECTION USING NANOPORES Public/Granted day:2015-12-24
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