A system for sterilizing a physical space, such as a hotel room. The system generates and distributes heated air to the physical space to elevate the temperature of the space to a level sufficient to achieve a desired sterilization effect of eradicating insects and microoganisms. The system is portable and self-contained. The system includes a hydrogen fuel cell that generates electrical power. An electrical system conditions and stores the electrical power and supplies stored electrical power to the system components and peripherals. System components include a source of hydrogen, a heater, an air distributor, and a filter. Peripherals include a UV light source and an aerosol dispenser. The combination of heat, UV light and aerosol disinfectant effectively eradicates insects, microorganisms, allergens, and odors in the physical space.