发明授权
![Antibody-drug conjugates comprising substituted benzo[e]pyrrolo[1,2-α][1,4]diazepines](/docs/US/2023-04-18/US11628223B2/abs.jpg.600x600.jpg)
- 专利标题： Antibody-drug conjugates comprising substituted benzo[e]pyrrolo[1,2-α][1,4]diazepines
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申请号： US16651501申请日： 2018-09-28
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公开(公告)号： US11628223B2公开(公告)日： 2023-04-18
- 发明人: Narihiro Toda , Yusuke Ota , Fuminao Doi , Masaki Meguro , Ichiro Hayakawa , Shinji Ashida , Takeshi Masuda , Takashi Nakada , Mitsuhiro Iwamoto , Naoya Harada , Tomoko Terauchi , Daisuke Okajima , Kensuke Nakamura , Hiroaki Uchida , Hirofumi Hamada
- 申请人： DAIICHI SANKYO COMPANY, LIMITED
- 申请人地址： JP Tokyo
- 专利权人： DAIICHI SANKYO COMPANY, LIMITED
- 当前专利权人： DAIICHI SANKYO COMPANY, LIMITED
- 当前专利权人地址： JP Tokyo
- 代理机构： Foley & Lardner LLP
- 优先权： JPJP2017-190713 20170929
- 国际申请： PCT/JP2018/036252 WO 20180928
- 国际公布： WO2019/065964 WO 20190404
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; C07D487/20 ; A61K47/68 ; A61P35/00 ; C07K16/30
![Antibody-drug conjugates comprising substituted benzo[e]pyrrolo[1,2-α][1,4]diazepines](/abs-image/US/2023/04/18/US11628223B2/abs.jpg.150x150.jpg)
摘要：
A novel antibody-pyrrolodiazepine derivative and a novel antibody-pyrrolodiazepine derivative conjugate using the same, comprising substituted benzo[e]pyrrolo[1,2-a][1,4]diazepines represented by the [Formula 24], [Formula 25], [Formula 26], and/or [Formula 27].
公开/授权文献
- US20200261594A1 ANTIBODY-PYRROLOBENZODIAZEPINE DERIVATIVE CONJUGATE 公开/授权日：2020-08-20
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