Invention Grant
- Patent Title: 5-HT2A agonists for use in treatment of depression
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Application No.: US17349255Application Date: 2021-06-16
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Publication No.: US11633390B2Publication Date: 2023-04-25
- Inventor: Jesper Langgaard Kristensen , Anders Asbjørn Jensen , Emil Märcher-Rørsted , Sebastian Leth-Petersen
- Applicant: Lophora ApS
- Applicant Address: DK Copenhagen
- Assignee: Lophora ApS
- Current Assignee: Lophora ApS
- Current Assignee Address: DK Copenhagen
- Agency: Duane Morris, LLP
- Agent Gregory M. Lefkowitz; Brandon A. Chan
- Priority: EP19207578 20191107
- Main IPC: A61K31/452
- IPC: A61K31/452 ; A61P25/24 ; A61K31/397 ; A61K31/40 ; A61K31/451 ; C07D205/04 ; C07D207/08 ; C07D211/22 ; C07D211/34
Abstract:
The present invention relates to agonists of the 5-HT2A serotonin receptors and their medical uses. In one aspect the invention relates to 5-HT2A agonists of formula (I). In second aspect, the invention relates to selective 5-HT2A agonists of formula (II). In another aspect, the invention relates to mixed 5-HT2A/5-HT2C agonists of formula (III). In yet another aspect, the invention relates to 5-HT2A agonists for use in the treatment of a depressive disorder, more particular a 5-HT2A agonist for the use in the treatment of treatment-resistant depression.
Public/Granted literature
- US20220062257A1 5-HT2A AGONISTS FOR USE IN TREATMENT OF DEPRESSION Public/Granted day:2022-03-03
Information query
IPC分类:
