A display panel and a display drive method thereof, and a display device are provided. The display panel includes a plurality of display regions and a plurality of scan drive circuits, the plurality of display regions includes a first display region and a second display region that are parallel to each other and do not overlap with each other, and the plurality of scan drive circuits includes a first scan drive circuit and a second scan drive circuit, the first and second display regions are connected to the first and second scan drive circuits to respectively receive a first light-emitting control signal, and the display drive method includes: individually adjusting a pulse width of at least one of the first light-emitting control signal and the second light-emitting control signal to adjust the light-emitting durations of light-emitting elements of the first and second display regions within one display period, respectively.