A bladder for an article of footwear extends from an anterior end to a posterior end and includes a first chamber disposed in an interior region of the bladder and a second chamber at least partially surrounding the first chamber. The first chamber includes a first interior void having a first pressure and the second chamber includes a second interior void having a second pressure. In some implementations, the second chamber includes a plurality of lobes arranged in series and each having a first end, a second end, and an intermediate portion disposed between the first end and the second end. Each lobe has a greater thickness at the intermediate portion than at the first end and the second end, such that each lobe tapers from the intermediate portion to the first end and the second end.