Invention Grant
- Patent Title: BRD4-kinase inhibitors as cancer therapeutics
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Application No.: US16894010Application Date: 2020-06-05
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Publication No.: US11643396B2Publication Date: 2023-05-09
- Inventor: Ernst Schönbrunn , Nicholas J. Lawrence , Harshani R. Lawrence
- Applicant: H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC.
- Applicant Address: US FL Tampa
- Assignee: H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC.
- Current Assignee: H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC.
- Current Assignee Address: US FL Tampa
- Agency: Meunier Carlin & Curfman LLC
- Main IPC: C07D239/48
- IPC: C07D239/48 ; C07D491/048 ; C07D405/14 ; C07D403/12 ; C07D405/12 ; C07D403/14 ; C07D401/14 ; C07D403/04 ; A61P35/00 ; A61K45/06
Abstract:
Disclosed herein are compounds that are inhibitors of BDR4 and their use in the treatment of cancer. Methods of screening for selective inhibitors of BDR4 are also disclosed. In certain aspects, disclosed are compounds of Formula I through IV.
Information query
