Invention Grant
- Patent Title: Neuroactive steroids and compositions thereof
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Application No.: US16887887Application Date: 2020-05-29
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Publication No.: US11643434B2Publication Date: 2023-05-09
- Inventor: Francesco G. Salituro , Maria Jesus Blanco-Pillado , Marshall Lee Morningstar
- Applicant: Sage Therapeutics, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Sage Therapeutics, Inc.
- Current Assignee: Sage Therapeutics, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Honigman LLP
- Agent Andrew N. Weber; Jonathan P. O'Brien
- Main IPC: C07J43/00
- IPC: C07J43/00
Abstract:
Provided herein is a compound of Formula (I):
or a pharmaceutically acceptable salt thereof, wherein R1a, R1b, R2a, R2b, R3, R4a, R4b, R5, R6a, R6b, R7a, R7a, R11a, R11b, R12a, R12b, R16a, R16b, R19, R11a, R22, RX, RY and n are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I) and methods of using the compounds, e.g., in the treatment of CNS-related disorders.
or a pharmaceutically acceptable salt thereof, wherein R1a, R1b, R2a, R2b, R3, R4a, R4b, R5, R6a, R6b, R7a, R7a, R11a, R11b, R12a, R12b, R16a, R16b, R19, R11a, R22, RX, RY and n are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I) and methods of using the compounds, e.g., in the treatment of CNS-related disorders.
Public/Granted literature
- US20200377547A1 NEUROACTIVE STEROIDS AND COMPOSITIONS THEREOF Public/Granted day:2020-12-03
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