- 专利标题: Expansion of γδ T cells, compositions, and methods of use thereof
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申请号: US16610398申请日: 2018-05-03
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公开(公告)号: US11655453B2公开(公告)日: 2023-05-23
- 发明人: Richard Beatson , Adrian Hayday , Oliver Nussbaumer , Richard Woolf , Maria Luisa Iannitto , Natalie Mount
- 申请人: King's College London , GammaDelta Therapeutics Limited
- 申请人地址: GB London
- 专利权人: King's College London,GammaDelta Therapeutics LTD
- 当前专利权人: King's College London,GammaDelta Therapeutics LTD
- 当前专利权人地址: GB London; GB London
- 代理机构: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- 优先权: GB 07048 2017.05.03
- 国际申请: PCT/EP2018/061413 2018.05.03
- 国际公布: WO2018/202808A 2018.11.08
- 进入国家日期: 2019-11-01
- 主分类号: C12N5/0783
- IPC分类号: C12N5/0783 ; A61K35/17 ; A61K45/06
摘要:
The present invention provides methods of expanding γδ T cells from a non-haematopoietic tissue source. Further provided are compositions of expanded γδ T cells and methods of using the expanded γδ T cells (e.g., apart of an adoptive T cell therapy).
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