A computer-implemented method, a computer program product, and a computer system for multi-path networking with a feature of multiplexing. One or more computing devices or servers configure wrappers for respective ones of applications and run the applications with the wrappers preloaded to the respective ones of the applications. The wrappers establish communication through one or more alternative paths between wrapped applications, where the one or more alternative paths are parallel to an original path between the applications. The wrappers exchange data between the applications through either the one or more alternative paths or the original path. The wrappers finalize connections through the one or more alternative paths, in response to all the data being exchanged.