A wireless earphone incorporates a wire antenna having a form factor driven innovative antenna shape that minimizes antenna detuning caused by user interactions with the earphones. The wire shape, diameter, and distance of the wire antenna from the printed circuit board (PCB) are selected for an acceptable tradeoff between antenna bandwidth and radiated efficiency. By inserting an end through a through-hole of the PCB, the wire antenna is electrically connected to a multi-layer PCB without traditional approaches such as springs, pogo pins, and the like. An antenna holder further secures the antenna within a thin profile housing for precise placement and manufacturing consistency. A PCB-specific RF VIA geometry is also utilized for partial impedance matching of a transmission line to the wire antenna. In addition, a more constant impedance is maintained along the transmission line connecting a radio device with the wire antenna.